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Mafia Syndrome 

A condition characterized by an overwhelming sense of paranoia at having one's back exposed or unprotected; The person who sits in the back of the class, or the back of the restaurant, or in the corner, like a real creeper, who is afraid of spontaneous back stabbings by strangers or hit men; So named because of the old days where mafia members never sat at a place in a restaurant where they could be attacked or caught unawares by someone coming in the front door. It has since carried over to the modern day, where it isn't really necessary, (unless you live in a third world country or maybe Iraq or North Korea) but somehow still affects people in all walks of life.
Waitress: "Sir, will this table be alright?"

Creeper: "No... no, let me have that booth that's in the corner...and turn out the light over the table please. I normally eat in the dark."

--

Waitress to Hostess: "Why didn't you warn me that creep has mafia syndrome?"
Mafia Syndrome by Kivixalla May 23, 2010
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Super Mario syndrome 

When a guy feels strong romantic and intimate feelings to a girl that barely acknowledges his existence, and chases after her, much like Mario does in many of his video games for Princess Peach.
Person #1: Did you see how hard Jack's trying to get Stacy to fall for him?
Person #2: Sounds like he has severe Super Mario syndrome to me.

Mario Syndrome 

When a person has to 1 UP any story you tell, no matter if it's something big, small, celebratory, or traumatic.
You know that girl, Sarah? I swear she has Mario syndrome. I can't tell her a single thing without her sharing her own experience.
Mario Syndrome by anonymous June 3, 2023

Mario brothers syndrome 

The act of making stupid mistakes over and over (usually at the same point) while trying to perform what should be a simple task. This most likely happens when doing things in a rushed manner.
Mario Brothers Syndrome:
Basically, in the original Super Mario Brothers for the Nintendo Entertainment System, trying to get through certain worlds hastily causes errors on the players part. Like hitting a turtle sideways and dying instead of jumping directly on it.

Marie Antoinette Syndrome 

When someone in the ruling class has everything they need and is oblivious to the fact that many of the common people are suffering from a lack of basic necessities

When Marie Antoinette was told that the peasants were starving and didn't even have bread she responded "Let them Eat Cake!"
John Boehner and Mitch McConnell represent classic cases of Marie Antoinette Syndrome, their Congressional Health Care plans provide them with the best Health Care in the world, but they have fought against making health care available to the masses, appearantly unconcerned that thousands of Americans die every year because they can't afford basic health care.

Mario Party Syndrome 

What happens to the palm of your hand after playing minigames in Mario Party that involve rotating the joy stick. Symptoms include soreness in the palm and/or a red mark where the joy stick was rotated.
After playing Mari Party for several hours, Jose began to experience Mario Party syndrome on his right hand.

"50 Turn Mario Party" Syndrome 

The tendency to get sick of an extended game or movie marathon faster than you would if you were actually doing something for its regular duration.

Most often seen when someone suggests you play a 50 turn game of Mario Party, or all the tracks in a racing game, or watch all the extended versions of the LOTR.
"I'm already sick of this LOTR marathon"

"Dude, we haven't even gotten halfway through Fellowship yet. You're definitely suffering from "50 Turn Mario Party" syndrome."