Top Definition
An expression for a girl who always seems like a good idea to date in the beginning but always ends up breaking your heart in the end, multiple times.

(Originally coined from The Medic Droid's song 'The Killer Anna'.)
-Tom, why the hell would you get back together with her for the 4th time?! You know she's a killer anna.
-Dude, I know I know, but this time she said it would be different.
-Whatever.
by imJBD August 13, 2010
3 Words related to killer anna

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