Irritable Male Syndrome 

Irritable Male Syndrome (IMS) is the male equivalent of the female hormone change during menstruation. Believe it or not but men's hormones change every month too, this results in mood swings similar to those women experience. Luckily it doesn't cause men to bleed through their pecker.

Michael is suffering from Irritable Male Syndrome a.k.a his man period.

Irritable Male Syndrome by SkinnedHamster August 5, 2015

Irrefixable 

Ya just can’t fix it

1. That is seriously broken
2. Yeah yeah I know it’s irrefixable
1. Couldn’ta said it better myself

Irrefixable by UnqualifiedGiraffe October 12, 2020

Irritable Bitch Syndrome 

The persistently inflammatory condition of a bitchy person, resulting in poor absorption of positive experiences while they express frequent yet pointless bitchiness. Habitual of certain men and women.

The beautiful, sunny day at the pricey amusement park was a nightmare with her Irritable Bitch Syndrome flaring up every ten minutes.

Irritable Bitch Syndrome by JayKayOfToronto February 24, 2009

Irresistible 

Too attractive, too tempting, and too powerful to be resisted. Also her beauty and intelligence can't be resisted!

Her actions speaks so loudly you can't hear her speak.

That Samantha Roundtree is sooo irresistible!

Irresistible by MzLadyS23 December 25, 2016

irresistible 

cant be resisted, you cant resist the urge to have that person or thing

that guy is soooo irresistible!!! hes just yummy

irresistible by jas1989 November 17, 2010

irresistable 

someone that u cant take your eyes off off and you are drawn to and someone who is oober cute

david k is sooooo irresistable! i just cant get enough of him

irresistable by courtney h. December 16, 2006

Irritable Jowel Syndrome

A chronic disease suffered by a good friend of mine. Symptoms include yakking it up when he should be keeping his pie-hole shut.

Ken:Hey Norm, remember the time you, me & the 3 Mormon chicks....
Norm: Hey Ken, STFU! My wife's right here and doesn't need to hear about how I banged that Morman every day for 2 straight months in a row! You f*ing have irritable jowel syndrome, dude~~

Irritable Jowel Syndrome by Bangboy December 26, 2009