Top Definition
The persistently inflammatory condition of a bitchy person, resulting in poor absorption of positive experiences while they express frequent yet pointless bitchiness. Habitual of certain men and women.
The beautiful, sunny day at the pricey amusement park was a nightmare with her Irritable Bitch Syndrome flaring up every ten minutes.
by JayKayOfToronto February 24, 2009
7 Words related to Irritable Bitch Syndrome

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