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1. The paradoxical state of being both a homosexual (homo) and a motherfucker (mofo). One who is both latently gay and depraved enough to have sex with his own mother.

2. A devoted male fan of rock group Good Charlotte.
"What a homofo!"

"I can't believe Dan could be such a homofo!"

"You goddamn homofo."
homofo by Setkino October 5, 2007
Related Words

homofoshowork 

homework which is gay, pointless and takes up too much time. Basically all forms of homework.
My homofoshowork took hours last night
homofoshowork by Rapechel April 25, 2009
Folk music made by homosexual peoples.
Did you here Hotel Floor Pizza's new homofolk album
homofolk by homofolk January 24, 2023
Hot Mother Fucker
Girl 1: DAMN look at Will today! hes looking fineee
Girl 2: oh yeah hes a homofo
homofo by Will the homofo November 12, 2010
Homsexual and a mofo at the same time
You're one big homofo
homofo by virushark October 14, 2003

homofobo 

A Mix Of Homo, Mofo, Hobo Homfobo
Look At That Homofobo
homofobo by Josh Man November 1, 2006