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1.
1. A degenerate induvidual. Characterised by a willingness to decline in financial, mental and physical health on an ongoing basis, often by means of his or her chosen party favor.

A degen is one step above the dero or derelict in the scale of madness.
Scozz Walker crawled out from under a miniskip after sacking a fistful of tacktacks and a skinful of tang. He is the ultimate degen!
by ffmmmmfmm September 26, 2005
 
2.
Gambler, "degenerate" gambler. Refers to card players, racetrack bums, bookies, dice & craps shooters, proposition (prop) bettors. Gamblers consider other gamblers degens, but not themselves usually. Card players consider sports bettors "degens." Sports bettors consider slot machine players degens. Etc
by CJRogue September 30, 2012
 
3.
Stylish to the max. Any individual who can make friends with anyone
Dude. . .that stylin kid over there has GOT to be a Degen
by boise state March 05, 2009
 
4.
Any kind of person that has a hate-on for someone or some group for a reason they can't explain. Most everyone is a Degen in some respect.
Degen: Fucking kids who shop at Abercrombie are faggots.

Degen: Fucking kids who shop at Hot Topic are faggots.

Degen: Fucking emo pussies are faggots.

Etc...
by Spoof January 26, 2005
 
5.
fucking computer science retard. all loosers. short for degenerate fuck. no style. spotty, wear glasses, play on their computers all day
All computer science students are degens
by johnnyboy May 29, 2003