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ants in your pants 

To be nervous or anxious or jumpy; to be unable to sit still.

If you had 'ants' (small insects) in your 'pants' (clothing) you would probably feel like jumping around.

Synonym: antsy
1) The children had ants in their pants, so we took them outside for some exercise.

2) Would you please stop tapping your foot?! You must have ants in your pants!
ants in your pants by VAKI5 May 10, 2005
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