Is the old way that new drivers were instructed (before the airbag advent) to place their hand at the steering wheel. I.e.: The left hand in "10" (clock position) and the right in position of "2".
Instructor: "Once you had the engine working, engage the first gear, and drive with your hands 10 and 2."
First two rules of an infamous site on the Internetz. They both mean that you're not allowed to talk about the site. Ironically, rules 1 and 2 have become a defining feature of the site, essentially making them useless whenever cited.
Reference to Fight Club, whose two first rules were both 'Do not talk about Fight Club'. May be used for anything secret, particularly an organization or group of some sort.