Top Definition
The act of making the vagina moisten, usually by entering with your tongue or penis.
I heard that girl likes it when dudes activate her pussy.
by commander b3 July 15, 2009
1 more definition
To begin the smoking of marijuana. Often said when someone holds up the lighter in a closed fist towards you.
your stoner friend: ACTIVATE
by high rolla' July 03, 2010

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