YOFO 

You only fuck once

E: OMG, that wedding was so fun! I'm so happy for them.
J: Yeah, but I totally heard the bride and groom YOFO'ed... Poor girl.
E: Oh man, no YOFO. Never YOFO!

YOFO by Paperscissorsrockme September 12, 2013

YOFO 

You only flunk once...

You can and will only flunk photography once.. YOFO

YOFO by yeeaaahhbuddy November 13, 2012

YOFO 

The YOFO 🤟🖕, or better known as the "Yo, fuck off", is an action of supreme consciousness where the person performing the YOFO shows the receiver the "Yo" symbol (an upward facing spiderman gesture 🤟) followed by a instant change to the holy middle finger🖕.

Beta female - "Oni-chan, uWu :3"
Sigma male - YOFO 🤟🖕

YOFO by NikkuR January 6, 2022

Yofo 

latin slang for vagina

White guy: yo dude, did u see that girl?

latin guy: si vato, tenia una mini skirt y se le miraba todo el yofo!

White guy: que?! O.o

latin guy: la Pussy guey!

Yofo by Torched Up: JoJo ThunderBoltz April 9, 2010

top over the pop mock yofo 

to top something you recently did with something even better, thus giving people something to look forward to.

Are you going to top over the pop mock yofo your gig next year and give an even greater concert?

top over the pop mock yofo by HyggeligKar January 9, 2008

yoforia 

A magical feeling, similar in kind to euphoria, that occurs after nomming delicious frozen yogurt topped with a variety of fresh fruits and other toppings.

This feeling of yoforia is almost as intense as the first time I had sex...with you...

yoforia by Commodore84 April 15, 2010

yofomoious 

Really cool,wicked,taste good,delicious,andsmart.

"Thats really yofomoious!" and "He is really yofomoious." and "He's really smart,no he's yofomoious."

yofomoious by Jordan Cummins December 28, 2007