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1. a wiseguy, a highly ranked individual in a crime family
2. wiseguy, a smartass/Jackass
3. wiseguy, a book by Nicholas Pileggi
1. He's a wise guy, he's untouchable
2. The guy over theres being a real wiseguy
3. did you read wiseguy yet?
by Q.T. September 06, 2004
A mob guy, a mafioso.
by Anonymous September 10, 2003
a 'made man' in the mafia
in 'the sopranos' tony's crew are wise guys
by dirrtyboi101 June 28, 2005
1. A smart aleck.
2.One who makes snide, sardonic and concieted comments and genereally acts like an arrogrant bastard.
3. The best retort ever.
Person 1: Hey you idiot.

Person 2: Oh, a wise guy, eh?

Person 1: What?

Person 2 (aggressively): I said wise guy!
by not a wise guy September 07, 2006
awise guy is a member of this thing of ours, more commonly know as the Italian Mafia. not neccessarily a made guy but you got to have association widem.
"That guy living down the road, he's a wise guy, he's untouchable"
by Wise Guy? April 09, 2009