The term has come to loosely refer to being high on speed, as well as unfortunately children who have been exposed to meth amphetamines in utero, parodied on shows including South Park.
1. Tweak- to touch something up, fiddle with the finishing touches or make tiny little changes.
2. Tweak- To perfect in an Obsessive Compulsive Disorder-ish way
3. Tweak- Little over-caffinated kid with various bizarre nervous-tics who lives in South Park
4. To be on some type of speed and be any/all of the following: --Highly aggitated, wide eyed, and angry/overly irritable --To be as paranoid in a mouselike manner; rapid breathing, weird twitchy and/or panic-ey movements/responses --To be euphoric as a motherfucker whilst on some type of upper( which is usually taken in a rather large amount to induce such energized and super-human like euphoric oddness)
--Just really fucking cracked out, in any way, as long as its super conspicuously performed behavior that is commonly associated with crackheads/random speed-heads --To be using or experiencing some feeling or difference caused by the use of Methamphetamines
2. "I just gotta tweak this and THIS AND THIS AND THIS and this and OHH NO now this..."
3.How do I make an example of this? If you don't watch the fucking show, what does the example matter to your familiarity?
4. "Dude your fucking twitching and grinding your teeth like a goddamned crackhead, wouldya quit pacin' around freaking about shit all quarter-eyed like that?"
::shaking, wide-eyed in the corner, head tucked behind huddled knees:: "Icantcomeout--gassp. Thh-thhuah--THEYLL GET ME!"::
"OH-MY-GOD- YOUGUYSWATCHICANRUN - AND! - READTHISBOOK -ATTHESAMETIME! WITHOUT RUNNINGINTOSTUFFHOLYCRAP! I'm god." ::scampers about rapidly, limbs a-flurry and a manic smile plastered to their face::
"Dude, seriously, it's probably just because you're a meth-head"
2) to use amphetamine or methamphetamine.
a grip of anphetamine pills or a couple of lines of meth can cause you to tweaki all night.