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5.
The Big Three are Fatty (fat), Ugly, or Facial Hair. (n): A term used to define the three characteristics a female must NOT meet to be considered hot.
-Dude last night this chick tried to slip me a roofie.
-Was she one of the Big Three?
-No, hot brunette.
-Nice.
by The Supreme Ben December 12, 2006
 
1.
When a women gets to the age where she acquires: the sagging breasts, the dry vagina, and the false teeth.
Aaron: What about that one over there?
Phillip: Na na, I can see two of The Big Three from here.
by ajohnw March 20, 2008
 
2.
The Big Three includes of Chris Bosch (#1), Dwayne Wade (#3) and LeBron James (#6) who all were acquired in the 2010 offseason to play for the Miami Heat. This triple threat can be referenced as the best acquisition of players since The Boston Three Party.
by kingstroke89 October 31, 2010
 
3.
A group of three guys who think they are a big deal. Each of the three talk shit about the other two, mostly in attempt to win over certain girls to get with. They also emotionally resemble women as well as play them. They're total bro's, and total assholes. They're a bfd.
Kian:Dude, did you hear that Lauren and Etelle have BOTH gotten with all of the guys in the big three?
Benjamin: No way dude, getting the big three is such a big deal.
by spittersarequitters July 27, 2011
 
4.
Phone. Wallet. Keys. The only three items that matter when waking up after a night of extensive drinking
Hey man did you check your pockets for the big three?
by FlatbushZ June 23, 2013