said in a manner where it almost sounds like one syllable. it is short for Senora, such as when it is used in Spanish classes when preceding the last name of a female instructor. however, it is most often used by the lazy as "Sra." and works just as well as Senora and it is spelled with the period which is also known to be an abbreviation for Senora, but when spoken, it isn't pronounced "Senora."
"Hey Sra. Rodriguez"