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1.
A state of inebriation involving a combination of drugs and alcohol.

From the Kid Cudi song 'Embrace the martian'
Got wasted last night, then me and the boys headed home to a fifty bag and got sluted.
by Jinxreducing April 14, 2009
 
2.
a girl who fucks all your friends then dates virgins cuz your dick was so big
Shelly is sluted
Shelly is sluted
Shelly is sluted
Shelly is slutedSh
by ddddddddddddddddddd May 07, 2006