Top Definition
One of the many slang terms for the drug OC, that is Oxycontin.
I'll pick up 2 80's of sizzle and some thizzle for my hoes.
by Iloveoc September 16, 2005
1. To smoke weed, to burn.
2. To be engaged in an activity
What ya sizzling?
by Bagg April 17, 2003
The sound of something roasting.
Those barbecued pork ribs sure did sizzle on my grill.
by AYB February 18, 2003
To humorously mock or humiliate someone with a well-timed joke, diss or comeback.

Noun form: the aforementioned joke, diss or comeback.

See also roast

"I just had to sizzle Knooch about that chubby chick he frenched last night."
by Creff von Crinklepants December 07, 2005
Crack Cocaine or The act of smoking crack cocaine.
"Are you cooking that shit yet?, I wanna sizzle!" or "That crazy fool went all the way down to the grind to score some sizzle"
by ChroNICK AZ May 13, 2006
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