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1. sizzle
One of the many slang terms for the drug OC, that is Oxycontin.
I'll pick up 2 80's of sizzle and some thizzle for my hoes.
by Iloveoc Sep 16, 2005 share this
2. Sizzle
Sister. Used with fo shizzle.
Fo shizzle my sizzle
by anyonomous Mar 28, 2004 share this
3. sizzle
To humorously mock or humiliate someone with a well-timed joke, diss or comeback.

Noun form: the aforementioned joke, diss or comeback.

See also roast

"I just had to sizzle Knooch about that chubby chick he frenched last night."
4. sizzle
1. To smoke weed, to burn.
2. To be engaged in an activity
What ya sizzling?
by Bagg Apr 17, 2003 share this
5. sizzle
To sizzle someone is to walk around a public place poking people as they walk by while saying "SSSSSSSSSSSSSS."
Girl 1: Ooooo sizzle this guy coming up!

Girl 2: Okay!

*Pokes guy* SSSSSSSSSSSSS

Guy: *Looks* Wtf?

Girls: You've been sizzled.
6. sizzle
Alternative word for 'serious'.
1. Are you sizzle?

2. John won't tell me if he's sizzle or not.
7. sizzle
Crack Cocaine or The act of smoking crack cocaine.
"Are you cooking that shit yet?, I wanna sizzle!" or "That crazy fool went all the way down to the grind to score some sizzle"
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