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1.
Word that can be used in substitution for "shit", when usually (but not always) preceded by "Oh" or something of that nature.
Oh shizzo, that cop just blew right by me!

Ah shizzo, we're out of kool-aid.
by skyliner53521 August 30, 2009
 
2.
Generally some stupid person. An alternative insult to words like Clegghead, plonker or jebend.

Derived from the word shizzle.
Bob Cheel...you are a shizzo!
by and the Hams November 03, 2007