An affliction that affects people and caused them to spit out random stuff that has nothing to do with the current conversation!
Two chicks on the exercise bikes at the gym;

Chick 1: Man, this new workout is really making me drop some serious poundage! Or maybe it’s the South Beach diet working its magic…

Chick 2: Oh really? Good for you…I still can’t see the difference on my ass yet…

Chick 1: Well I’m totally gonna hit Victoria’s Secret at the end of the month and surprise my boo with some sexy lingerie…

Chick 2 starts singing loudly: ‘All the Single Ladies! All the Single Ladies!’

Chick 1: WTF was that? Can you please stay on topic...

Chick 2: Sorry dude…that was like total randomitis!

by lady lynxx April 01, 2009

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Top Definition
A fictional disease that can be used as a reason for doing something inexplicably stupid,and well,random.
Adam:Dude!Why did you smear that sour cream all over the couch?
Rex:Oh,just got me a case of the randomitis
by Caoimhe8168 July 09, 2009

The Urban Dictionary Mug

Lotsa space for your liquids.

Buy the mug

The Urban Dictionary Mug

Lotsa space for your liquids.

Buy the mug

The Urban Dictionary Mug

Your favorite word on a white mug.

Create a mug

The Urban Dictionary Mug

One side has the word, one side has the definition. Microwave and dishwasher safe. Lotsa space for your liquids.

Buy the mug

The Urban Dictionary T-Shirt

Soft and offensive. Just like you.

Buy the t-shirt

The Urban Dictionary T-Shirt

Smooth, soft, slim fit American Apparel shirt. Custom printed. 100% fine jersey cotton, except for heather grey (90% cotton).

Buy the t-shirt