An truncated version of the phrase "perfectly fucked", similiar to fubar, and snafu perfucked is a situational modifier used to describe an event that ends in catastrophe, or disaster.
"At the time eating eight cupcakesin a row seemed like a good idea, but soon Wade's stomach became perfucked"
fucked over by puke in some way, whether it be as a result of alcohol consumption or pathological affliction--can refer either to the state of continual vomiting or the mess produced by such vomiting
A) Yo what's up man?
B) *vomits on self noisily*
A) Wow you're totally pukefucked.