pendejo (derived from Spanish, spelled "pen-deh-hoe") stands for someone who is a really retarded dumbass, has mental obstructions or someone without the ability to do anything right.
hoe is a woman (sometimes man) who is promiscuous and has sex with everyone no matter what.
It has no real use rather than insulting someone, instead of calling them hoe or pendejo you just call them pendehoe
"you are a retarded stupid piece of gay shit, ahahaha lol"
"you are a pendehoe, lolz"
-a man raped an old man
"you are a stupid ass only gay people do that"
Of course she did! Pen De Hoe!
2. Girl-How did I do?
Guy 1- Eh, you were alright.
Guy 2- Ah, Pen De Hoe, lets get out of here.