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1.
M2L2 is an acronym used by urban & Semi-urban population of INDIA to denote the expression of disrespect and disapproval towards the subject. Its full form is "muh mein le le" (Take inside your mouth) :D

Warning: It is not an abuse...its just an expression !! :P
Eg 1:
Ramu: yaar teri file complete ho gyi hai to meri file main diagrams bana de bhai please !
Shamu: m2l2, itna vella nahi huin main.

Eg 2:
Ramu: yar college main kal maths ki class hai 10 baje, attend karne aa jaio
Shamu: m2l2, tu pagal ho gya hai.
by Hacker_M2L2 December 26, 2010