Internet slang for "laugh my poop out", it can be used figuratively or literally.
You did WHAT to your grandmother?!? lmpo.
by Prima B. Goode July 23, 2004
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Nerd: OMFG THAT NEW POKEMON CARD IS KEWL!
Kid: Pokemon is crap, lmpo.
by JordanM February 12, 2005
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Laughing my posterior off

The classy version of lmao
Robert: Oh Charles, I am just oozing money! I am so rich, it's funny!

Charles: Good show, Robert, good show! lmpo!
by ChigglyWiggly August 27, 2011
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Tess: I can't say lmao considering i have no ass. . . . .i have pancakes so I say lmpo.
by Smileygonewrong April 25, 2009
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Laugh My Pants Off

For all those Christians who don't use profanity but would love to be cool

instead of LMAO(laugh my ass off)
thats was funny...LMPO
by 1PRINCE*! January 1, 2009
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