Top Definition
The formation of a blood clot (thrombus) inside a blood vessel in a man's lower intestines, obstructing the flow of blood through the circulatory system. Caused by aggressive or repeated anal sex.
Chris never thought his love for being a bottom bitch would result in a case of Homothrombosis.
by Geeewhiz June 28, 2009
5 Words related to Homothrombosis

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