ESAD Share definition Flag an acronym used to quickly tell someone to leave you alone and go away, taken from the first letter of each word in the phrase Eat Shit And Die. Person 1: You are working to slow.Person 2: ESAD!!Person 1 walks away feeling hurt or rejected. ESAD by Fritzy30 November 21, 2011 0 0 Get merch Get the ESAD mug. Buy Now — $32.95 See more merch