DooDoo Mouse Share definition Flag 1. A term used to describe someone who lacks intelligence 2. One who is RETARDED Person 1: Deeeeeeeerrrrrpyderpppp Person 2: Shut up, DooDoo Mouse... DooDoo Mouse by Christina the Terminally ILL Giraffe October 24, 2006 0 0 Get merch Get the DooDoo Mouse mug. Buy Now — $32.95 See more merch