Top Definition
Having a notably large butt that catches the attention of others anywhere you go.
"WHOA! Look at her butt! Clearly, she's got a case of that Bigbutt-itis."

"My Bigbutt-itis prevents me from fitting into normal sized jeans."
by IWantAnAPlease? November 15, 2011

Free Daily Email

Type your email address below to get our free Urban Word of the Day every morning!

Emails are sent from We'll never spam you.