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Very strong marijuana strain with easily noticeable THC crystals, which are often mistaken for cocaine crystals by people with single figure IQ's
Guy 1: Man that chronic I bought yesterday was laced with cocaine
Guy 2: Thats not cocaine you dumbass, those are THC crystals.
chronic by thearchitect November 25, 2007
Chronic has two different definitions varying on your location.

East Coast: Weed (Marijuana) that is laced with Cocaine to give an added effect

West Coast: The finest weed available with no seeds or any shit
East: I'm feeling suicidal, lemme get some chronic

West:I'm looking to get some chronic, none of that crappy bullshit
chronic by Madman September 14, 2004
1.) One of the stronger strains of marijuana. It is actually NOT used to describe just any sort of good weed, there is a certain type, usually indica, that is labled chronic. It won 3rd place at the 1994 High Times Cannabis Cup.

2.) Marijuana laced with cocaine.
1.) "And a phat ass J of some bubonic chronic that made me choke. Shit this ain't no joke." - Snoop Dogg


2.) Joe rolled an eight with a nick of coke and we smoked a phat ass chronic blunt.
chronic by Kidd Flow February 20, 2005
1. Very potent, high-grade marijuana. Typically categorized by it's lack of seeds (sensimilia) and high concentrations of white or opaque crystals (trichromes)

2. In a very acute or intense state of being
The chronic I had the other day helped me mellow out after a hard days of work.
chronic by sinthetek March 16, 2005
Chronic is buds of cannabis (weed) that is extremely potent. In sight, Chronic has crystals of THC in plain sight. May or may not have seeds. Extremely sticky when touched.
chronic by Chron Lungs May 13, 2005
A type of marijuana. Chronic is grown under perfect conditions which makes the THC (marijuana's active ingredient) level go through the roof. This results in a much stronger drug and a greater smell.
Chronic by Street Pharmicist August 28, 2003