GUPO 

Gay Until Proven Otherwise

GUPO: This is code for straight girls to describe that super hot guy at the pub who has clean fingernails, is wearing a pink floral shirt BUT is drinking beer from a can. 'Do you think he'll ask me out?' 'Be careful, he's definitely GUPO'.

GUPO by BUPO January 7, 2012

GUPO 

Gay Until Proven Otherwhise. Someone who hasn't been seen dating anyone of the opposite sex for quite some time/ever. Friends or colleagues will assume that such a person is gay until they have seen "proof" to the contrary. Mostly used about women.

Derived from the thumb rule of justice: "Guilty until proven otherwhise."

Oh, you know, nothing much - so the usual. She's a GUPO if I've ever seen one.

GUPO by WillVisitIndia July 8, 2010

GUPO 

Gay Until Proven Otherwise

Ayo, that nigga is GUPO as fuck.

GUPO by Successful Black Man September 23, 2013