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A Japanese acronym standing for "Time, Place, and Occasion".
Neku: Sakura, I think we should break up.

Sakura: What?!?!

Sakura's Friend: Breaking up with Sakura at her birthday party? Terrible TPO on Neku's part.
TPO by Sasuke_Smiles_Scare_Me December 13, 2009
Related Words
totally pissed off about a situation, or on somebody.
Sooraj, Bharat were walking back from the office. Sooraj, looked annoyed at the amount of work he'd to finish. He hated Chinese and he lost the bet with Bharat, so he had to do what Bharat said.

Bharat: How was ur day,man?

Sooraj: Don't talk me into it,OK?

Bharat:Fine.We eat Chinese today, remember that?

Sooraj:Not today,man. I beg you.

Bharat:But, why? Remember, you lost the bet.

Sooraj:Please, not today.

Bharat:Why, TPO?

Sooraj:Yeah, whatever.
tpo by pantula June 19, 2009
TPO is an acronym standing for Thoroughly Pissed Off; this means that you are about as far from happy as it is possible to get and the world and his brother can fuck right off and die.
I've just spent the morning fixing another fuck up by that fuckwit Malcolm and I am TPO.
TPO by AKACroatalin February 3, 2021
i gotta get to a bathroom, i got a TPO
tpo by Anonymous June 15, 2003
True Players Only. For instance, a 60" plasma tv would be TPO, or anything else that is ridiculously expensive.
The Rims on that guys car are TPO.
tpo by Mark Q August 29, 2005
The Player Of.

Used frequently for online gaming where a character/toon name is better recognized than the name of person playing the game.
Person A: "Hey, it's me, Heu."
Person B: "Who...?"
Person A: "TPO Francine Kirby."
TPO by Kudda October 16, 2009