Commonly used in sports, to "take it to the house" means to score a point in a big play. The term is almost always used in the context of American football, usually after a player gets a large breakthrough play and takes it all the way to the endzone after a long run.

This term is also applicable in American football when a player catches an interception and runs it all the way for a touchdown (coined as pick six) or when a player returns a field goal kick that was either short or blocked (coined as kick six after the 2013 Auburn-Alabama game).
"And he's gonna take it to the house for the win!"
by Psedoudnym January 4, 2017
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to do it to it; go all out and do it real properlike. real horrorshow.
Hell yeah we're going out tonight; we're gonna take it to the house.
by Marco St. John May 3, 2005
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To go home to take a poop, instead of at work, school, stores, restaurants, etc.
Bill: "Dude, I gotta shit in the worst way!"

Ted: "Then go, dude- Wal Mart's bathrooms aren't that dirty."

Bill: "Screw that bro, I've gotta take it to the house!!"
by J3553 January 16, 2009
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Sexual terminology for take your woman to the house and get your game on
Damn guy, take it to the house.
by HA! September 19, 2003
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What Mason McAlexander says while recieving a blow job.
Mason-Oh yeah take it to the house
Stephanie-Shut the fuck up! I'm only here because you're paying me!
by ADM September 21, 2003
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