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vibe cleanse 

a process where you rid yourself from all bad vibes caught after an encounter
riri: Did you enjoy that convo with that dude?
lily: No, i needed a big, fat, vibe cleanse.
vibe cleanse by hunnydew May 7, 2020

acai berry cleanse 

Yet another diet craze in the never ending quest to avoid simply eating healthy and exercising, it combines the all natural and recently discovered health benefits of juice from the acai berry (unsold prune juice left over from the 80's) with the effects of receiving no less than 50 spam emails a day on the topic (vomiting from shear disgust) to rid the body of unhealthy toxins (any recently eaten food) and unnecessary weight (water)
Dana: I need to lose that last 5 pounds.

Paul: Have you tried the new acai berry cleanse? It's all natural....like sticking your finger down your throat...but without all the negative connotations that comes with bulimia.
acai berry cleanse by calihog August 3, 2009

Juice Cleanse

Expensive bottles that harbor an inexpensive carrot/broccoli liquid that more or less help with a BM (bowel movement)/or more commonly known as a shit
"I really wanted to drop 8 pounds before a party this weekend so I thought what better way to shit out your weight than with a juice cleanse."

Facebook Cleanse 

To erase unwanted or unneeded people on your facebook friends list. Usually a result of having 300+ friends but only talking to a fraction of them. Basically a friends cleanse but exclusive to Facebook.
I decided to have a Facebook cleanse, now my friends list is only half it's original size.
Facebook Cleanse by Roger_5000 December 30, 2011

smegma cleanse 

"Come here you smegma cleanse. My penis is dirty."
smegma cleanse by ken69 June 23, 2009

regional cleansing 

The business process of terminating an entire geographic location. Sometimes done to move people to corporate headquarters, of as part of a bigger plan to outsource jobs, or a cost savings plan to move jobs to a cheaper region (e.g. India).
The first thing Jeremy did after joining the company, was to perform "regional cleansing" of the Redmond, Washington development group. Jeremy showed up Monday and told everyone that their jobs were being eliminated. They had one month to look for new jobs in other corporate locations.
regional cleansing by Judi Uttal October 1, 2005