Top Definition
1. The brain and central nervous system.
2. The administrators, operaters, and programmers in a computer network.
3. Sometimes used in science fiction to define computer hardware that has been integrated into the brain.
1. (non-slang)
2. (non-slang)
3. no example given
by thegestalt October 25, 2004
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The brain.
Your hardware and software seem to be fine, so I can only assume that your wetware is fucked up.
by teej October 16, 2003
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The name of a 1988 science fiction novel by Rudy Rucker, which explores the merger between human beings and biocybernetic technology.

Winner of the 1988 Philip K Dick award for science fiction.
In the beginning the humans built the Boppers.
Then the Boppers took over and built themselves.
And now the Boppers are making humans.

With a soft spot in their microchips for Earthlife's info-mix stew, the moon-based robots have worked out how to infuse DNA's wetware with their own software code...
by flynnbar June 21, 2007
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an imitation of OTM|Bejebus
calling someone : you wetware
Bejebus you wetware
by Baracas January 15, 2003
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A soggy meat computer known as the brain.
You would be doing humanity a favor by making your wetware permanently inoperable.
by Madih September 06, 2017
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