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Combining cocaine and a light downer type pharmaceutical (ie diazapam) (1g\5mg). The tranquilizers take the edge off the coke high without detracting from it. But check yourself, you gon' die
"Whenever I use coke i get way too live fam"

"Bro just mash this valium up with the coke, chop it and bump it. The slowcaine is the shit bro, you buzzing but you stay cool, balance"
Slowcaine by Purple pain September 17, 2020
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The slang term for ketamin only the real dudes know
"who's up for round 18 of the slowcaine"
slowcaine by abundancechaos June 12, 2018
Related Words
slowcaine is a term used when a person is already high on downers (e.g: benzodiazepines, opi*id painkillers, or any other substances that slow down brain activity) and he/she starts to ingest Cocaine.
The high is often described as a calming, very euphoric “high” that doesn’t last long.

(Mixing any nervous system stimulant with a/or multiple nervous system depressant can be extremely dangerous and it puts a huge stress on your body)

Being “slowcained” can be extremely dangerous as the upper can mask the effects of the downers in your system (e.g: Valium, Oxycodone, Xanax, Hero*n, Codeine, Morphine ), which can k*ll you when the Cocaine wears off.
William: What’s good? you look like you didn’t sleep well last night.
Derrick: Yeah man, i was up all night long poppin’ Percocets, then i decided that i will get slowcained as f*ck so i bought an 8ball of that fishscale snow, but after finishing it i couldn’t sleep so i took 10 Valium to come down
slowcaine by YvesSaintPercocet July 20, 2025

Smocaine 

Smocaine is a crack detective who is literally on heroin on the job but is still the best cop on the force. He doesn't play by the rules, but that's his strength.
"He's a damn good cop when he's straight and sober, but somehow the heroin gives him an edge". Quote from Smocaine 3
Smocaine by Nitro Dubbz March 6, 2018

snowcaine 

A drug kids can have.easy to find in winter
Where my snowcaine seller

snocaine 

snortin on some snocaine!
snocaine by Caine April 21, 2003

Blowcaine 

Slang term for cocaine. Also the name of the Jake&Jackie Show fan forum.
Dope Fiend #1:"Dude I got some poppers and amyl nitrate and some nose candy. Wanna get fucked up?"
Dope Fiend #2:"What the fuck is 'nose candy'? If you mean blowcaine then lets go just leave those poppers and amyl nitrate outta the mix."