1. a female sibling

2. a female friend that acts like, loves you like, and treats you like a sibling.
I don't have any sisters.

My best friend is like a sister to me.
by King's Daughter June 20, 2005
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There are two type of sisters, ones the good friend kind, she'll always seem to be there somehow when you need help and it just seems like a good friendship instead of having a sibling. You and your sister would often ask each other for favours and sometimes pull a couple pranks on each other and can keep a secret, it might seem strange sometimes but at the same time natural.

The other kind is the very annoying type, she is most likely very annoying and would really embarrass you in front of your friends, unintentionally, and intentionally. often quite arrogant and takes every advantage to crush your social life and confidence.
1. my friend carries his sister's stuff to school for her, in return he asks to borrow money from her whenever he has a sudden urge to raid a vending machine for candy.

2. my friend "Ok seriously, every time i come over to your house your sister is screaming, and now she's gonna come to your grad and probably scream because unlike you , she didn't get a date for the dance? That's rough."

Me "yea i know, she's gonna ruin it for me."
by sdjhfbskd July 11, 2008
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A smart, beautiful sibling who always has good advice for her brothers, who are always acting like buffoons.
Brother: Oh no! I have nothing good to wear on my date with the school slut!

Sister: I think you should dump her, you might get an STD. But if you insist on dating her, you should wear your black slacks and this white button up shirt.

Brother: Thanks Sis! You know what, you're right! I will dump her, and I'll ask the new girl out instead! Thanks a bunch!

Sister: You're welcome.
by Barb Ann October 27, 2006
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one who is always true to you, no matter what. one who will always love you. one who will trust you. your best friend for life. your gaurdian angel.
angel sister
by VicLyn1244 April 29, 2011
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Somebody who has the same mother or father as you, can be half, whole, or annoying. Determined to be just like you, or bother you.
Also any female who is acting like a sister.
My sister is reading over my shoulder...
You better stay offa my man, sistah.
by i luv cOnNFoRmItY! March 24, 2004
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(Verb) To terminate something in an abrubt or unexpected fashion. Derived from the sudden ending of Sergio's (BE) performance ("Sister") at the Eurovision songfestival in 2002.
After Jack was diagnosed with several STD's, he sistered his relationship with Svetlana.

"Art. 3: Watching midgetporn during working hours will sister this contract of employment and nullify all duties of the employer."

The problem with urinating from the Eifeltower is that you can't sister if the security guard catches you.
by Nasemeister December 12, 2012
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1.A black female
2.A word that can be used in a greeting to show friendship of a black female.
1.Is the girl you was talking about a sister? (Sista.)
2. What's up mah Sista?
by JR. December 12, 2004
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