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pneumonoultramicroscopicsilicovolcanoeconiosis 

1. A condition induced by the inhalation of excessive dust particles, in which the lungs of a human being fill up with tiny particles, having severe detrimental effects on the body.
2. The best freakin word on the planet
The doctor sighed, and said reluctantly, "I'm sorry to say, but it seems that you have been afflicted with the disease of pneumonoultramicroscopicsilicovolcanoeconiosis."
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pneumonoultramicroscopicsilicovolcanoeconiosis 

This is the longets word in the ENTIRE English Language. Its 45 letters long and 19 syllables... Count it out
He's right... it is the best freakin'word on the planet.

supercalifragilisticexpialidocious floccinaucinihilipilification antidisestablishmentarianism hippopotomonstrosesquippedaliophobia pneumonoultramicroscopicsilicovolcanoeconiosis llanfairpwllgwyngllgogerychwyrndrobwllllantysiliogogogoch 

Supercalifragilisticexpialidocious floccinaucinihilipilification antidisestablishmentarianism hippopotomonstrosesquippedaliophobia pneumonoultramicroscopicsilicovolcanoeconiosis Llanfairpwllgwyngllgogerychwyrndrobwllllantysiliogogogoch is my first word combo!

pneumonoultramicroscopicsilicovolcanoconiosis 

An inflammation of the lungs caused by microscopic grains of certain types of rock.

*NOTE* This word was actually coined in a deliberate attempt to be the longest word in the english language, although you would be hard-pressed to find it in the language dictionary as it is a medical/scientific term.
"Dude, now that I've learned how to spell antidisestablishmentarianism, what am I going to do to make people think I'm smart?"

"Quiet man, I'm trying to name this condition we discovered today. Its an inflammation of the lungs caused by microscopic grains of certain types of rock."

"Hey, I smell opportunity! How long could we make this word?"

"Pretty long...I suppose we could stretch it to pneumonoultramicroscopicsilicovolcanoconiosis"

pneumonoultramicroscopicsilicovolcanoconiosis 

A: What's the wifi password?
B: It's on the back of the router.
The router: pneumonoultramicroscopicsilicovolcanoconiosis

pneumonoultramicroscopicsilicovolcanoconiosis'd've'ly'yaint'nt'ed'ies's'y'es'nt'ed'ies's'y'es'nt't're'ing'able'ric'ive'al'nt'ne'm'll'ble'al 

the longest possible grammatically correct EVER.
man i really pneumonoultramicroscopicsilicovolcanoconiosis'd've'ly'yaint'nt'ed'ies's'y'es'nt'ed'ies's'y'es'nt't're'ing'able'ric'ive'al'nt'ne'm'll'ble'al ing hate this guy

pneumonoultramicroscopicsilicovolcanoconiosis 

1. A disease gotten from inhalation of diminative particles of silica or quartz.
Pneumono - Lung
Ultra Microscopic - Very small/fine
silico volcano - igneous, silica
coniosis - disease
; Black Lung
In the mid 1880's, miners would get pneumonoultramicroscopicsilicovolcanoconiosis.