In Spanish, and in many Spanish speaking countries, "nene" is a term of endearment used for males ("nena" for females).

It can be used toward each other amongst lovers, family, friends and even sometimes strangers in a joking or "light-hearted" manner, depending on the context and how its used in the Spanish speaking country of origin where the person saying it is from.

It can be equivalent to saying "honey", "hun", "sweetie", "babe", "baby", etc.
Wife: "How was your day at work nene?"
Husband: "Exhausting.. I'm tired and hungry. What's for dinner mami?"

Mom: "Hurry up and get ready for school nene. You're gonna be late!"
Son: "But I don't feel so good. I think I'm sick" *coughs*

Friend (guy): "Damn, look at Carmen.. She's so fly."
Friend (girl): "You still crushin' on her nene? Man, you've liked her since 6th grade! Why don't you just ask her out??"

Cash register older lady: "Find everything in the store ok nene?"
Kid: "Yes Ma'm"
by Mamisonga25 January 24, 2011
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a word a girl uses for her novio. it's like honey or baby.
i love my nene
by gaby June 28, 2004
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Nene is a bad bitch that holds her on and she is fearless
Damn she bad her name gotta be nene.
by habits2000 October 8, 2019
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In 2K10 hes the best player, better then kobe.
"Holy Shit! Cris has the nene squad on 2k10."

"I love me some nene"
by tohuntspys April 13, 2010
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nene short for courtnie is mostly made by a smaller sibling who cant pronounce courtnie
nene is my older sister
by momlovercj 21 July 1, 2015
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The sweetest most gorgeous girl in the world! Friendly to all but keeps your deepest darkest secrets and never tells. Her long beautiful hair, rocking body, and model-like face turns the head of more than a few boys'. Her crazy personality draws many friends. Having a NeNe in your life makes everything perfect!
She's so perfect, she must be a NeNe!
by Frans4Lyf January 6, 2013
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