When someone does methanphetimines so long they don't know how to behave in society. The drunk meth cook violating probation that kills a young man while she was talking on her cell phone hooking up her next victim, while driving thru town.! A destructive drug user.
"That woman was f'n methed up"!
by JeannieHotPants March 4, 2008
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An action or the result of an action that is caused by a meth user that's high on methamphetamine.
Bro, did you see the geekers house up the street? It's methed up!

TweekersGeekersMethamphetamine
by J Milluh September 8, 2018
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THE CONDITION OF BEING SO STUNG OUT THAT THE IDEA OF SELF GROOMING HAS BEEN LOST AND REPLACED WITH INSATIABLE URGE TO FIND THE BUGS THAT CRAWLING AROUND UNDER YOUR SKIN BY BURROWING HOLES WITH YOUR FINGERNAILS.
OR AN IDEA SO COMPLETELY FUCKED UP THAT IT MUST HAVE BEEN FORMED ON A METH BINGE.
MAN THAT CHICK IS METHED UP.
by MONGO TRAINER November 13, 2018
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to be on meth while under the disco ball at cheap skate.
I'd choose to be methed up over the prostitutes at the front door any day
by guesshowmanysticks April 20, 2011
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How a person on meth says messed up. Wrong, aint right
Did u see her face? Thats methed-up! U really methed-up this time man
by Thottie2Hottie September 9, 2017
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When witnessing an act that could only be committed by someone who has not slept in as many days as they have left teeth.
"Did you here Tom's mom asking to suck me off for money"

"No I didn't, dang that's methed up"
by gisimisim December 19, 2008
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