Where your penis becomes the size of an atom and makes you sexually attracted to fat naked men. During Leo syndrome you pass through 72 stages each becoming progressively worse. Throughout these stages a few of the symptoms are your bones will melt, you will gain a massive cheese helmet, you will be covered in acne head to toe and you will become a retard on the level of Amy burleigh. This disastrous syndrome is un-cureable and will result in a lonely and very sad life.
Kristy: heyyy Leo, oh wait shit u have Leo syndrome ARGHHH
Leo:*cries and becomes retarded*
by Janice is fit April 21, 2019
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leo Syndrome happens when you get onto the 72 stage of James syndrome. Your hole body completely shuts down and your penis gets so small that it disappears and your rectum explodes
Kristy: Leo you have leo syndrome

Leo: better fucking die then
by Big big Dave March 30, 2019
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When an Asian male does not take care of his personal hygiene, these people do not shower often and always smells of body odor.
Oh that Asian guy over there smells terrible and doesn't look like he knows what a shower is, he probably has Leo Wang Syndrome
by Bruhrack Obama February 6, 2020
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Leo syndrome is a serious condition where your penis gets so small it goes inside you and then your rectum explodes

And Kristy gets shot in the head by a meatball
Luke: my FUCKING DICK IS SO SMALL

Mia: I know you have leo syndrome
by Big big Dave March 30, 2019
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