A retarded person who is uncomfortable around complicated surroundings.
"IM HAVING ISSUES WITH MY TISSUES" said the retard having issues with tissues.
by Pwa 'm' Pwa November 17, 2009
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Not sure how this has no definition yet and generally isn't a more common used figure of speech, because it works in multiple ways.
So, basically

1: If you don't spill anything on the floor, you're not going to have to clean it up
"Can I trust you to work alone for a bit?"
"Yeah bruh, no issues, no tissues"
2: If there's no problems, then you don't need anything to wipe the tears out of your face

"I'm fine"
"You been crying, no issues no tissues sis"
3:

A way to respond to someone inquiring requests from you that you currently don't have any
"Dude, should I get you anything from da store?"
"No issues, no tissues homeboy"

4:
When someone expects one of your experiences to have been way more intense than they really were

"Fell down de stairs"
"Ahh shit musta sucked homie"
"Nah brotha, no issues, tissues"
Look above cunt
No issue no tissue
Ya happy urban dic
by Petra Jansen November 10, 2019
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People who love telling you all thier problems. Drama queens and kings. People to avoid. Energy drainers. P
"X" argh they have more issues than tissues
by auzkiwi July 13, 2016
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People who love telling you all thier problems. Drama queens and kings. People to avoid. Energy suckers.
Nigel has more issues than tissues
by auzkiwi July 13, 2016
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People who love telling you all thier problems. Drama queens and kings. People to avoid. Energy drainers. P
by auzkiwi July 13, 2016
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People who love telling you all thier problems. Drama queens and kings. People to avoid. Energy suckers.
Nigel has more issues than tissues
by auzkiwi July 13, 2016
Get the more issues than tissues mug.