A subtle blend of glitch and situation, often used in reference to a computer problem of moderate to extreme magnitude.
Hello, IT department, we have a glitchuation. My outlook crashes every time I try to send the Million Dollar Widget proposal.

Sorry guys, there is a glitchuation with tonight's poker plans. Wife is NOT leaving town this weekend.
by Ghost211 April 13, 2012
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A major calamity, the result of a critical mass of otherwise minor annoyances.
Phone call from Kathleen Sebelius to President Obama on the launch day of the ACA website: Mr. President, we have a glitchuation!
by Mr.Scopes November 2, 2013
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