fapigue 

That strain/pain you feel on your penis when you fap too much within a short period of time. (i.e. Fap fatigue)

This was experienced by many during 2014's Fappening.

Dude 1: "Dude, have you seen the latest Fappening leaks?"
Dude 2: "Yeah, man. I'm was so fapigued last night."

fapigue by masterball63 September 23, 2014

Template fatigue 

In the corporate world, templates are often provided by more senior people as a means of requesting and gathering information. The template are portrayed as an attempt to make the process easier, when in reality they make things harder.

These people in headquarters keep sending me templates to fill out on different topics. There are so many of them and in different versions that I’m suffering from template fatigue.

Template fatigue by M-regulator October 12, 2018

nigger fatigue 

"Nigger Fatigue" refers to an overall tiredness towards the 'Black Lives Matter' Riots & Looting, kneeling monkeys in NBA & NFL, as well as the overall degeneracy and shameful filth tried to market as 'music' by black 'artists and rappers'.

I really have that Nigger fatigue.

nigger fatigue by wyk1ng September 12, 2020

nigger fatigue 

A state of physical or mental exhaustion in response to overabundance of culture and news pertaining to people of color, particularly African Americans.

Bro, I swear Americans just can't stop talking about niggers. I'm getting fucking nigger fatigue reading this shit holy fuck

nigger fatigue by JamaicanBaconXO November 20, 2021

femme fatigue 

Femme fatigue is what a man reaches when he’s burned out with pursuing women only to realize again and again that they are primarily all the same with regards to their sense of entitlement and the obstacles he must endure just to get some stink on his dick. This whole process costs him time and money and most always reminds him that the greater majority of women justify a man's staying single and redundantly invokes the same question: Who the hell would put up with this bitch?! Still, the situation repeats as his need for sexual gratification builds up and he’s forced to once again subject himself to the social meet up and dating scenes to re-endure his limits of frustration and sacrificial finances required to continue this bullshit.

Hey dude, are you headed out tonight?

No, I’ve got a bad case of femme fatigue and don’t have the patience for their bullshit. I may just avoid the whole fucking game and call a hooker.

femme fatigue by Big Ed Moustapha September 11, 2011

Stupid fatigue 

The condition where dumb no longer surprises you or awes you with it's levels of ignorance, it just exhausts you.

After watching the debate, I had to go to bed with a bad case of stupid fatigue.

Stupid fatigue by Russell Nash February 12, 2012

Social Fatigue 

Social Fatigue occurs when a person is overwhelmed by being put into far too many social situations for their comfort, often resulting in boredom or annoyance of those around them.

Social Fatigue can result from over-use of social networking sites (Facebook, myspace) or various online forums where clashing opinions can wear out a persons tolerance faster.
Controversial topics such as Politics, religion, or worn out Meme's can further propel the spiral to Social Fatigue.

Social Fatigue also occurs in MMO's (Massivly Multiplayer Online games) where grouping and other social activities are required to make progress in the game.

At some point a sufferer of Social Fatigue just wants to be left alone, because they have reached the conclusion that most people are just plain stupid.

After a forum discussion on Zombies, Bacon...and the conclusion of zombie-bacon, Robert had Social Fatigue and didn't care if the world spiralled in to the sun tomorrow... so long as these people went with it.

Social Fatigue by Loxzen January 12, 2010