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Internet's Down Syndrome 

A temporary condition brought on by the lack of internet connectivity and characterized by irritability, fidgeting, lack of focus, a general feeling of helplessness and occasionally exercise.
Steve: What's up with the glazed look on Meredith's face?

Brad: Well, she likes to start her day reading Perez but we have no connectivity and slipped into an acute case of Internet's Down Syndrome.

chow down syndrome 

a portmanteau of the words "chow down" and "down syndrome," meaning the loss of mental acuity following a hefty meal; aka food coma.
Is he alright?

He's fine. Just a bit of chow down syndrome.

system of a down syndrome 

being completly obsessed with system of a down
dude he has system of a down posters all over his house i think he has system of a down syndrome.

delta down syndrome 

A name referring to the fight group known as Delta. This is used when describing any flight in a JROTC unit. It can used to describe any flight or group regardless of the actual flight its self. Can be used when singing degrading songs while marching. This is only used if and when a flight is made up of complete idiots, and at least a quarter of the flight has a form of Down syndrome.

down syndrome motherfucker 

When you are really pissed off at someone who is normal(not retarded in anyway) and has a slightly down syndrome look face, you yell at them "what the fuck are you looking at, you down syndrome motherfucker!! This releases stress and puts a great big smile on your face. Try it today!
No examples needed for down syndrome motherfucker. You can fit it in with just about anything.

Down-syndrome Hammer Fiesta 

When an individual with Down-syndrome loses his/her shit, and proceeds to annihilate anything in reach with a hammer of some sort.
Did you see the news today?

Fuck the news.

Well Alabama was annihilated by a Down-syndrome Hammer Fiesta

Alright? Who gives a flying fuck about Alabama?