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Direct Client Connection, a protocol used on IRC to send files between users, create private chats, and make a whiteboard for shared drawing. The DCC handshake is sent through the server (with CTCP), but the file/chat/whiteboard session takes place over a direct connection between the clients--hence the name.

Can also be used as a verb, meaning to send a file using DCC.
"Hey man, DCC me that video of Fred Durst eating his own shit."
by NSFMr2K December 29, 2003
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