A hazing ritual, typically on a football team, in which a bottle of sports drink is forcibly inserted into a lesser member's anus.
"John got the buffalo run at the party last night... Gatorade bottle. I've still got bloodstains on my carpet."
"We're going to buffalo run Smith for fucking up the game!!"
"The captain buffalo'd his lineman."
"We're going to buffalo run Smith for fucking up the game!!"
"The captain buffalo'd his lineman."
by T. K. October 15, 2006
a variation of the runs you get after eating a massive amount of buffalo wing sauce that results in burning pain around your buttocks
by Spicy Pepper March 2, 2010