As the name suggests, it comprises of the two most sacred words the world has ever seen; boob and virginity. Girls lose this when they first let another person ( guy or girl, man or woman, child or animal ) grab or feel up their bare chest (Note: over the bra, means that you're still a boob virgin). It's kind of like losing your virginity but only with your chest.
In short it is also referred to as BV. BVs can be given and taken only once in a lifetime.
Girl 1: Supp girl, did you have crazy time on your date last night???
Girl 2: Yes I did, but I got carried away and lost my Boob Virginity to that guy. Before I knew it, his small hands were all over my chest.
Bro 1: Hey bud, How did the date last night go ? Did you get any action ?
Bro 2: Totes bro. I reached all the way to second base only to find out I took her Boob Virginity.
Bro 1: That's great man, looks like you had an amazing time.
Bro 2: It was all great until the time she head butted me for squeezing too hard.
While our lifespan is the number of years we will live, our healthspan is the number of healthy years we will have and our sexspan is is the number of years we will continue to be healthy enough to continue having an active sex life.
A lighthearted reaction upon receiving disappointing news of some sort. Usually something that isn't a particularly a big deal, esp. when it primarily affects someone else - sort of a mild schadenfreude. Sometimes doubled or tripled, and possibly said in a sing-songy voice for added comedic effect to imitate a muted trumpet, which is how the meme originated.