Yo that crack head down the street was tweaking fighting the air earlier tripping
by Vito March 14, 2017
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Somone tripping on a meth high. They are paranoid about staying up for a week straight seeing shadow people and such.
by BigPimppin6906 November 16, 2017
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A manner of which a person‘s actions and behavior suited them of being very out of pocket and very unorthodox
My husband was tweaking very hard last night after work
by Rico gwaap June 2, 2022
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To be high on methamphetamine. NOT hallucinates
He's so tweaked out.
by kush_ March 17, 2005
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Frantic and compuslive behaviour often associated with methamphetamine abuse (crank). People who regularly abuse crank may find themselves unable to stop a particular random activity like searching drawers, having sex, or putting things apart. This is called tweaking.
"Oh man last night was awesome, I was tweaking and fucked my girlfriend for 6 hours straight..."
by RoOophy July 8, 2004
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