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R.O.U.S's are Rodents Of Unusual Size. It comes from the 1980's movie Princes Bride, in the fire swamp scene where Buttercup and Wesley encounter the ROUS's. The rodents are about the size of a large dog.
R.O.U.S are like a Capybara. They are the worlds largest rodent.
by Mina72 August 18, 2011
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rou is beautiful, smart, helpful, and talented at everything. she is a very easy person to talk to. rou is mostly patient with everyone she meets. she has a big sense of humor and is just so welcoming. she will be the one to guide you. rou is an overall unstoppable person with a big heart who will always be there for you.
wow, is there anything rou can’t do?
by officialsmella May 04, 2020
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Rodents
Of
Unusual
Size
I was having sex with Alee in a hotel when I looked over my shoulder and saw a ROUS
by Eric Chin May 26, 2005
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Rou or R.O.U. stands for Routine Police Work
Lazy detective: Hey how'd you solve that burglary?

Not so lazy detective: R O U

Lazy detective: Huh?

Not so lazy detective: ROUtine police work bro, try it.
by pabluras March 11, 2014
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