A set of four cities on the Mississippi River including Davenport and Bettendorf of Iowa, and Moline and Rock Island of Illinois. It is debatable whether or not East Moline of Illinois is included. It is well known for being the headquarters of John Deere, Whitey's Ice Cream, the only place where the Miss. runs East-West, and an interesting flavor of both states.
"The Quad Cities is a fabulous place to grow up and raise a family."
by Romaniac August 12, 2005
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Redneck-ville located in the northwestern section, on the Mississippi River, of Illinois. Consists of 5 differint cities (ignore the "quad" part), of Moline, Rock Island, East Moline, Illinois, & Davenport, Bettendorf, Iowa. People from this part of the U.S. have much better values and morals than other big-city folk, like, say, New Yorkers.
Quad Cities? Oh, the one place I most likely won't get pick-pocketed and turn out to be a Democrat!
by Tirza Wynes February 24, 2005
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Orlando. Home of Quad City DJ's, 95 South, 69 Boyz and DJ Magic Mike.
by QuadCity May 12, 2007
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While the female is shitting on the toilet she is also giving a blowjob to the male standing in front of her
Dude, last night I got a Quad Cities Rambler from Stacy. We're throwing away ALL the Pepto in this house!!
by Mitchell Wharton October 17, 2010
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Any baseball player who is a big enough badass to play in tournaments in Arizona, California, Florida, Texas, and their home state of Iowa (except for Drew- but he's so amazing that he can live in the middle of nowheresville Illinois and still play for the Cobras).

They are also known for never losing.
Erika: Man our brothers are so freakin amazing @ baseball
Brian: Yeah that's why they play for the Quad City Cobras
by Bettdogs7 January 19, 2005
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