When you can’t fall asleep so you bust a fatty in order to go to bed
Dude last night I couldn’t fall asleep so I took some homemade nyquil!
by Papafluffdaddy December 26, 2017
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Take 3 shots of nyquil, leave the house for a year and a half, then return and take 3 more
"Why's Michael leaving? He's gonna black out"

"Oh he's doing the Nyquil Jordan. He'll eventually be back with someone who fucked Madonna"
by djmoy20 January 23, 2022
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The consumption of Nyquil to reach a desired effect, such as sleeping.
I had to resort to Nyquilling last night to finally get some rest.
by debpossible November 20, 2017
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When someone gets knocked out unconscious in a fight around a lot of people
"Dang, he just got nyquilled in front of everyone at the gas station!"
by Mystic Styles September 3, 2023
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